Motor Signs in the Prodromal Phase of Parkinson's Disease
Identifieur interne : 001060 ( Main/Exploration ); précédent : 001059; suivant : 001061Motor Signs in the Prodromal Phase of Parkinson's Disease
Auteurs : Walter Maetzler [Allemagne] ; Jeffrey M. Hausdorff [Israël, États-Unis]Source :
- Movement disorders [ 0885-3185 ] ; 2012.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Relatively subtle deterioration of the motor system likely occurs well before the patient meets established motor criteria for a clinical diagnosis of Parkinson's disease; ie, the occurrence of at least 2 of the cardinal motor deficits: bradykinesia, rigidity, tremor, and/ or postural instability. Powerful compensatory mechanisms may mask these clinical symptoms and make them difficult to identify and evaluate in the earliest stages of the illness. This review summarizes our current knowledge of motor signs that are thought to occur in the prodromal phase of Parkinson's disease and suggests how motor assessment batteries could be designed to detect these subclinical motor deficits with a high degree of accuracy and sensitivity.
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000196
- to stream PascalFrancis, to step Curation: 002B18
- to stream PascalFrancis, to step Checkpoint: 000133
- to stream Main, to step Merge: 001112
- to stream Main, to step Curation: 001060
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Motor Signs in the Prodromal Phase of Parkinson's Disease</title><author><name sortKey="Maetzler, Walter" sort="Maetzler, Walter" uniqKey="Maetzler W" first="Walter" last="Maetzler">Walter Maetzler</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Center of Neurology, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, University of Tuebingen</s1><s2>Tuebingen</s2><s3>DEU</s3><sZ>1 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>German Center for Neurodegenerative Diseases (DZNE), University of Tuebingen</s1><s2>Tuebingen</s2><s3>DEU</s3><sZ>1 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Physical Therapy, Sackler Faculty of Medicine, Tel-Avlv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="2"><inist:fA14 i1="05"><s1>Department of Medicine, Harvard Medical School</s1><s2>Boston, Massachusetts</s2><s3>USA</s3><sZ>2 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">12-0223378</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 12-0223378 INIST</idno><idno type="RBID">Pascal:12-0223378</idno><idno type="wicri:Area/PascalFrancis/Corpus">000196</idno><idno type="wicri:Area/PascalFrancis/Curation">002B18</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000133</idno><idno type="wicri:doubleKey">0885-3185:2012:Maetzler W:motor:signs:in</idno><idno type="wicri:Area/Main/Merge">001112</idno><idno type="wicri:Area/Main/Curation">001060</idno><idno type="wicri:Area/Main/Exploration">001060</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Motor Signs in the Prodromal Phase of Parkinson's Disease</title><author><name sortKey="Maetzler, Walter" sort="Maetzler, Walter" uniqKey="Maetzler W" first="Walter" last="Maetzler">Walter Maetzler</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Center of Neurology, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, University of Tuebingen</s1><s2>Tuebingen</s2><s3>DEU</s3><sZ>1 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>German Center for Neurodegenerative Diseases (DZNE), University of Tuebingen</s1><s2>Tuebingen</s2><s3>DEU</s3><sZ>1 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Physical Therapy, Sackler Faculty of Medicine, Tel-Avlv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="2"><inist:fA14 i1="05"><s1>Department of Medicine, Harvard Medical School</s1><s2>Boston, Massachusetts</s2><s3>USA</s3><sZ>2 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Compensation</term><term>Nervous system diseases</term><term>Parkinson disease</term><term>Posture</term><term>Prodrome</term><term>Sign</term><term>Strategy</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term><term>Pathologie du système nerveux</term><term>Signe</term><term>Compensation</term><term>Stratégie</term><term>Posture</term><term>Prodrome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Relatively subtle deterioration of the motor system likely occurs well before the patient meets established motor criteria for a clinical diagnosis of Parkinson's disease; ie, the occurrence of at least 2 of the cardinal motor deficits: bradykinesia, rigidity, tremor, and/ or postural instability. Powerful compensatory mechanisms may mask these clinical symptoms and make them difficult to identify and evaluate in the earliest stages of the illness. This review summarizes our current knowledge of motor signs that are thought to occur in the prodromal phase of Parkinson's disease and suggests how motor assessment batteries could be designed to detect these subclinical motor deficits with a high degree of accuracy and sensitivity.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Israël</li><li>États-Unis</li></country><region><li>Bade-Wurtemberg</li><li>District de Tübingen</li><li>Massachusetts</li></region><settlement><li>Tübingen</li></settlement></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Maetzler, Walter" sort="Maetzler, Walter" uniqKey="Maetzler W" first="Walter" last="Maetzler">Walter Maetzler</name></region><name sortKey="Maetzler, Walter" sort="Maetzler, Walter" uniqKey="Maetzler W" first="Walter" last="Maetzler">Walter Maetzler</name></country><country name="Israël"><noRegion><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name></noRegion><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Hausdorff, Jeffrey M" sort="Hausdorff, Jeffrey M" uniqKey="Hausdorff J" first="Jeffrey M." last="Hausdorff">Jeffrey M. Hausdorff</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001060 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001060 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:12-0223378
|texte= Motor Signs in the Prodromal Phase of Parkinson's Disease
}}
| This area was generated with Dilib version V0.6.23. |  |